Brian Sperl, M.D.

Indianapolis Gastroenterology and Hepatology

8051 S. Emerson Ave., Suites 150 & 200
Indianapolis, Indiana 46237

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Professional Bio

Dr. Brian G. Sperl holds an undergraduate degree from Indiana University and a Medical Degree from the Indiana University School of Medicine. In 1986, he finished his internship and residency at institution the Methodist Hospital of Indianapolis. He then moved to Kentucky to study gastroenterology, completing fellowship work in 1988 at the University of Louisville. At present, Dr. Sperl is a board-certified gastroenterology with certification from both the Board of Internal Medicine and the Board of Gastroenterology. In 2002, he began seeing patients at the Indianapolis Gastroenterology and Hepatology private practice group, where he served as the group’s former Treasurer.

Among other distinctions, Dr. Sperl is a member of the Indianapolis Medical Society and the Indiana State Medical Association. In addition to these local memberships, he is also involved with the American College of Gastroenterology (ACG). In his spare time, Dr. Sperl enjoys keeping himself physically active with outdoor activities such as hiking.


Dr Sperl and his staff are wonderful.

I always receive exceptional care when I am in the office. – Hilliary

He’s helped me know that I will survive this thing!

I’ve been a patient for 14 years, and have followed Dr. Sperl when he moved from one practice to another since I refuse to give him up. I moved away but willingly drive 1 1/2 hours so that I can still see him. He is an extremely compassionate and caring person who seems to care about the whole me, and not just about my intestines. He’s the only doctor I’ve ever been to that cares that I have a life outside his office. He always asks about my kids and my job.

He gives me praise when things are going great in my life, gives support when things aren’t so great, and tolerates my frustrations when I’m tired of having Crohn’s. He listens to my input about my disease and makes me feel that he and I are in a partnership. He takes my thoughts into consideration and fully discusses the various options with me so that WE can decide upon the best course of action.

Dr. Sperl understands how frustrating it is to have a disease. He’s helped me know that I will survive this thing!
– Anonymous

Nothing to add.

All personel were professional and showed courtesy. Dr. Sperl explained procedure before surgery. – Patrick

Dr. Sperl is a great asset to the Indy Gastro Team.

Being a nurse myself, at times we can be the more challenging patient. However the repor I have developed with Dr. Sperl is fantastic and he he a great professional. I woudl recommend him highly. I am always seen in a prompt manner and he is very attentive and understanding. I thank God he was put on my service in the hospital. Thank You Indy Gastro!


  • Barium Enema
  • Colonoscopy
  • CT Scan
  • Endoscopy
  • Fecal Immunochemical Test
  • Fecal Occult Blood Test
  • Polyp Removal
  • Rectal Exam
  • Sigmoidoscopy
  • Virtual Colonoscopy


  • Aetna
  • Indiana Medicaid
  • Anthem Blue Cross
  • United Healthcare
  • Cigna
  • Sagamore Health Networks
  • Indiana Health Network
  • Medicare
  • Advantage
  • Tricare
  • St. Francis Health Network